Bilateral Candida chorioretinitis following etanercept treatment for hidradenitis suppurativa

Treatment of hidradenitis suppurativa with etanercept injection.

OBJECTIVES To observe the effects of etanercept treatment on the cutaneous manifestations of hidradenitis suppurative (HS) and to evaluate physician and patient global assessment scores of cutaneous manifestations. DESIGN Single-center, randomized, prospective, double-blind, placebo-controlled study. SETTING Academic dermatology practice. PATIENTS Twenty patients with active moderate to s...

Hidradenitis suppurativa: a treatment challenge.

Hidradenitis suppurativa is a chronic, recurrent, debilitating disease that presents with painful, inflamed lesions in the apocrine-gland-bearing areas of the body, most commonly the axillary, inguinal, and anogenital areas. Etiology traditionally has been attributed to occlusion of the apocrine duct by a keratinous plug; however, defects of the follicular epithelium also have been noted. Contr...

A prospective clinical trial of open-label etanercept for the treatment of hidradenitis suppurativa.

BACKGROUND Medical therapies for hidradenitis suppurativa (HS) are often ineffective. Tumor necrosis factor-alpha inhibitors may be a potential treatment for patients with moderate to severe HS. OBJECTIVES We sought to evaluate the safety and efficacy of etanercept for patients with severe HS. METHODS We conducted a phase II clinical trial of etanercept (50 mg/wk subcutaneously) in patients...

Hidradenitis suppurativa.

BACKGROUND Hidradenitis suppurativa is a chronic, recurrent, suppurative cutaneous disease. Despite its incidence, optimal medical or surgical treatment remains unclear. This review describes the disease, ranging from pathogenesis to treatment and prognosis. METHODS Articles were sourced from PubMed and Medline, using the MeSH terms 'hidradenitis suppurativa' and 'acne inversa'. Selection of ...

Adalimumab for hidradenitis suppurativa.